On average, listings lease in the $20's per square foot per year. The San Luis Obispo submarket is going through a decrease in rates. In the last 3 months, the median rate fell $1 per sqft per year. That's a 3% decline in rent.
In the last 90 days, 56 listings have been listed, so you'll want to check back regularly for new listings. About 4% of the available leases in the San Luis Obispo are subleases, so you will probably have to focus your search on direct office leases. There aren't many listings below 2,000 square feet posted, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 1,420 sqft. Most properties in this area are close to 2 stories. Most buildings in this region were built in 2002 and are Class A.