On average, listings lease in the $50's per square foot per year. The Potrero Hill region is experiencing a a rise in rates. In the last 3 months, the median rate increased $3 per sqft per year. That's a 6% rise in rent.
Compared to the rest of the Bay Area market, the Potrero Hill submarket has greater rates, and you'll have to negotiate above asking rent to be in this hot region.
In the last 90 days, 10 listings have been made available, which means new availabilities might be leasing quickly. You'll want to be prepared to make an offer immediately. There aren't many listings below 2,000 square feet on the market, so finding a space for a small business might be tough.
Even though the median size is 3,000 sqft, there are still 0 leases below 2,000 sqft. Most buildings in this area are around 2 stories. Most buildings in this area were built in 1961 and are Class B.
Not much of the real estate is used for commercial space, so it might be hard to find office space. Health care is the dominant industry in this market. Most of the folk of Potrero Hill work from home. Commuting close to an hour a day is the norm for those who opt to reside in this part of town.