Compared to the rest of the Bay Area market, the Lower Nob Hill region has more expensive rates, and you'll have to negotiate above asking rent to be in this hot region.
In the last 90 days, 14 listings have been listed, which means new listings might be going fast. You'll want to be prepared to make an offer immediately. About 7% of the available leases in the Lower Nob Hill are subleases, so you will probably need to consider the implications of signing a direct lease with the building. There aren't many listings below 2,000 square feet on the market, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 1,400 sqft. Most buildings in this area are close to 4 stories. Most buildings in this area were built in 1915 and are Class B.
Not much of the real estate is used for commercial space, so it might be hard to find office space. Health care is the dominant industry in this area. Most of the folk of Lower Nob Hill work from home. Commuting approximately 15 minutes a day is the norm for those who opt to reside in this part of town.