The typical asking rate per listing is in the $70's per square foot per year. The Lower Nob Hill submarket is going through a an increase in rates. In the last 3 months, the median rate went up $6 per sqft per year. That's a 9% increase in rent.
Compared to the rest of the Bay Area market, the Lower Nob Hill region has greater rates, and you'll need to pay a premium to be in this hot region.
In the last 90 days, 16 listings have been listed, which means new availabilities most likley are leasing quickly. You'll want to be prepared to tour spaces as quick as possible. About 6% of the office spaces in the Lower Nob Hill are subleases, so you will probably need to consider the implications of signing a direct lease with the building. There aren't many listings below 2,000 square feet available, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 1,350 sqft. Most buildings in this region are approximately 4 floors. Most buildings in this region were built in 1915 and are Class B.
Not much of the real estate is used for commercial space, so it might be hard to find office space. Health care is the dominant industry in this market. Most of the occupants of Lower Nob Hill work from home. Commuting around 15 minutes a day is the norm for those who opt to reside in this part of town.