On average, listings lease in the $20's per square foot per year. The Poway region is experiencing a decrease in rates. In the last 3 months, the median rate decreased $6 per sqft per year. That's a 18% decline in rent.
Compared to the rest of the San Diego market, the Poway region has lower rates, so you should have no trouble finding a great deal in this depreciated region.
In the last 90 days, 25 listings have been listed, which means spaces might be going fast. You'll want to be prepared to make an offer immediately. About 8% of the listings in the Poway are subleases, so you will probably need to sign a longer term lease with the landlord directly. There aren't many listings below 2,000 square feet posted, so finding a space for a small business might be tough.
Even though the median size is 4,130 sqft, there are still 0 spaces below 2,000 sqft. Most properties in this region are close to 2 stories. Most buildings in this market were built in 1999 and are Class B.