On average, listings lease in the $40's per square foot per year. The East LA region is going through a a rise in rates. In the last 3 months, the median rate increased $10 per sqft per year. That's a 26% rise in rent.
In the last 90 days, 25 listings have come on the market, which means spaces are probably leasing quickly. You'll want to be prepared to make an offer immediately. About 4% of the available space in the East LA are subleases, so you will probably need to sign a longer term lease with the landlord directly. There aren't many listings below 2,000 square feet on the market, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 2,400 sqft. Most properties in this region are around 1 floors. Most buildings in this region were built in 1955 and are Class B.
Not much of the real estate is used for commercial space, so it might be hard to find office space. Information is the dominant industry in this area. Most of the residents of East LA work from home. Commuting close to 30 minutes a day is the norm for those who opt to reside in this part of town.