On average, listings lease in the $30's per square foot per year. The South Berkeley region is seeing a decline in rates. In the last 3 months, the median rate fell $24 per sqft per year. That's a 40% decrease in rent.
Compared to the rest of the East Bay market, the South Berkeley submarket has smaller rates, so you should have no trouble finding a great deal in this depreciated submarket.
In the last 90 days, 5 listings have been made available, which means listings are probably going fast. You'll want to be prepared to make an offer immediately. There aren't many listings below 2,000 square feet posted, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 1,250 sqft. Most properties in this area are close to 3 stories. Most buildings in this area were built in 1971 and are Class B.
Not much of the real estate is used for commercial space, so it might be hard to find office space. Health care is the dominant industry in this region. Most of the residents of South Berkeley work from home. Commuting between 20 and 25 minutes a day is the norm for those who opt to reside in this part of town.