The typical asking rate per listing is in the $10's per square foot per year. The James Island region is seeing a a rise in rates. In the last 3 months, the median rate went up $16 per sqft per year.
In the last 90 days, 1 listings have been listed, which means new listings most likley are going fast. You'll want to be prepared to make an offer immediately. There aren't many listings below 2,000 square feet available, so finding a space for a small business might be tough.
Even though the median size is 2,700 sqft, there are still 0 office spaces below 2,000 sqft. Most buildings in this area were built in 1962 and are Class C.