Most listings are in the $20's per square foot per year. The James Island region is going through a a boost in rates. In the last 3 months, the median rate rose $22 per sqft per year.
In the last 90 days, 6 listings have been posted online, which means office spaces might be leasing quickly. You'll want to be prepared to make an offer immediately. About 33% of the available space in the James Island are subleases, so you might be able to snag a great spot on a short term. There aren't many listings below 2,000 square feet on the market, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 1,540 sqft. Most buildings in this market are close to 2 floors. Most buildings in this area were built in 1981 and are Class B.
Not much of the real estate is used for commercial space, so it might be hard to find office space. Manufacturing is the dominant industry in this market. Most of the folk of James Island work from home. Commuting approximately an hour a day is the norm for those who opt to reside in this part of town.