Most listings are in the $30's per square foot per year. The James Island region is going through a a rise in rates. In the last 3 months, the median rate went up $33 per sqft per year. That's a Inf% increase in rent.
In the last 90 days, 2 listings have come on the market, which means spaces most likley are going fast. You'll want to be prepared to make an offer immediately. There aren't many listings below 2,000 square feet posted, so finding a space for a small business might be tough.
Even though the median size is 7,000 sqft, there are still 0 listings below 2,000 sqft. Most buildings in this market were built in 2013 and are Class C.
Not much of the real estate is used for commercial space, so it might be hard to find office space. Manufacturing is the dominant industry in this region. Most of the residents of James Island work from home. Commuting around an hour a day is the norm for those who opt to reside in this part of town.