The typical asking rate per listing is in the $10's per square foot per year. The Uptown region is going through a an increase in rates. In the last 3 months, the median rate rose $4 per sqft per year. That's a 27% increase in rent.
In the last 90 days, 18 listings have come on the market, which means leases most likley are going fast. You'll want to be prepared to make an offer immediately. About 6% of the available leases in the Uptown are subleases, so you will probably have to consider a longer term lease. There aren't many listings below 2,000 square feet on the market, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 2,410 sqft. Most properties in this region are close to 3 floors. Most buildings in this market were built in 1930 and are Class B.
Not much of the real estate is used for commercial space, so it might be hard to find office space. Health care is the dominant industry in this region. Commute by public transit is the most popular way to get to work amongst Uptown folk. Commuting approximately 15 minutes a day is the norm for those who opt to reside in this part of town.