On average, listings lease in the $20's per square foot per year. The Downtown Santa Fe region is going through a decrease in rates. In the last 3 months, the median rate fell $7 per sqft per year. That's a 22% decrease in rent.
In the last 90 days, 3 listings have been posted online, which means spaces most likley are leasing quickly. You'll want to be prepared to tour spaces as quick as possible. There aren't many listings below 2,000 square feet on the market, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 1,650 sqft. Most properties in this market are around 2 stories. Most buildings in this area were built in 0 and are Class B.
This area is fairly equally mixed residential and commercial. Professional services is the dominant industry in this area. Most of the residents of Downtown Santa Fe work from home. Commuting between 20 and 25 minutes a day is the norm for those who opt to reside in this part of town.