On average, listings lease in the $20's per square foot per year. The Durham region is going through a an increase in rates. In the last 3 months, the median rate increased $28 per sqft per year.
Compared to the rest of the The Triangle market, the Durham submarket has less expensive rates, so you should have no trouble finding a great deal in this depreciated submarket.
In the last 90 days, 76 listings have come on the market, so you'll want to check back regularly for new listings. About 112% of the available space in the Durham are subleases, so you might be able to snag a great spot on a short term. There aren't many listings below 2,000 square feet on the market, so finding a space for a small business might be tough.
Even though the median size is 3,700 sqft, there are still 0 new listings below 2,000 sqft. Most buildings in this area are close to 2 floors. Most buildings in this region were built in 1995 and are Class A.