On average, listings lease in the $20's per square foot per year. The Durham region is experiencing a decrease in rates. In the last 3 months, the median rate decreased $1 per sqft per year. That's a 3% decline in rent.
Compared to the rest of the The Triangle market, the Durham region has less expensive rates, so you should have no trouble finding a great deal in this depreciated region.
In the last 90 days, 40 listings have come on the market, which means listings are probably leasing quickly. You'll want to be prepared to make an offer immediately. There aren't many listings below 2,000 square feet available, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 2,240 sqft. Most buildings in this market are approximately 2 floors. Most buildings in this region were built in 1995 and are Class A.