On average, listings lease in the $10's per square foot per year. The Lowell submarket is going through a an increase in rates. In the last 3 months, the median rate rose $16 per sqft per year.
Compared to the rest of the Greater Boston market, the Lowell submarket has smaller rates, so you should have no trouble finding a great deal in this depreciated submarket.
In the last 90 days, 61 listings have been listed, so you'll want to check back regularly for new listings. About 20% of the listings in the Lowell are subleases, so you might be able to snag a great spot on a short term. There aren't many listings below 2,000 square feet available, so finding a space for a small business might be tough.
Even though the median size is 8,150 sqft, there are still 0 new listings below 2,000 sqft. Most buildings in this region are around 4 stories. Most buildings in this area were built in 1977 and are Class A.