Most listings are in the $10's per square foot per year. The Holyoke submarket is experiencing a decline in rates. In the last 3 months, the median rate fell $5 per sqft per year. That's a 25% decline in rent.
In the last 90 days, 3 listings have been posted online, which means office spaces are probably leasing quickly. You'll want to be prepared to make an offer immediately. About 300% of the office spaces in the Holyoke are subleases, so you might be able to sign a shorter term by taking over a previous lease. There aren't many listings below 2,000 square feet available, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 800 sqft. Most buildings in this area are close to 2 stories. Most buildings in this area were built in 1895 and are Class B.