Most listings are in the $40's per square foot per year. The Cambridge submarket is seeing a a boost in rates. In the last 3 months, the median rate rose $17 per sqft per year. That's a 50% increase in rent.
Compared to the rest of the Greater Boston market, the Cambridge region has greater rates, and you'll have to negotiate above asking rent to be in this hot region.
In the last 90 days, 32 listings have been made available, which means listings might be leasing quickly. You'll want to be prepared to make an offer immediately. About 6% of the available space in the Cambridge are subleases, so you will probably need to consider the implications of signing a direct lease with the building. There aren't many listings below 2,000 square feet posted, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 1,600 sqft. Most properties in this market are approximately 5 floors. Most buildings in this region were built in 1970 and are Class A.