On average, listings lease in the $30's per square foot per year. The Downtown Fort Collins region is going through a a rise in rates. In the last 3 months, the median rate rose $33 per sqft per year.
In the last 90 days, 6 listings have been posted online, which means new listings are probably leasing quickly. You'll want to be prepared to tour spaces as quick as possible. About 17% of the available space in the Downtown Fort Collins are subleases, so you might be able to find a shorter term or below market rent. There aren't many listings below 2,000 square feet on the market, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 530 sqft. Most buildings in this market are close to 2 stories. Most buildings in this area were built in 1904 and are Class B.
Not much of the real estate is used for commercial space, so it might be hard to find office space. Education is the dominant industry in this region. Most of the residents of Downtown Fort Collins work from home. Commuting around 20 minutes a day is the norm for those who opt to reside in this part of town.