On average, listings lease in the $20's per square foot per year. The Columbine submarket is experiencing a a rise in rates. In the last 3 months, the median rate increased $23 per sqft per year.
Compared to the rest of the Denver Metro market, the Columbine submarket has smaller rates, so you should have no trouble finding a great deal in this depreciated region.
In the last 90 days, 4 listings have been made available, which means listings most likley are going fast. You'll want to be prepared to make an offer immediately. There aren't many listings below 2,000 square feet available, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 1,340 sqft. Most buildings in this area were built in 1985.