On average, listings lease in the $10's per square foot per year. The East of 101 region is experiencing a an increase in rates. In the last 3 months, the median rate increased $20 per sqft per year.
Compared to the rest of the Silicon Valley market, the East of 101 region has smaller rates, so you should have no trouble finding a great deal in this depreciated region.
In the last 90 days, 4 listings have been posted online, which means listings are probably going fast. You'll want to be prepared to make an offer immediately. About 50% of the listings in the East of 101 are subleases, so you might be able to find a shorter term or below market rent. There aren't many listings below 2,000 square feet posted, so finding a space for a small business might be tough.
Even though the median size is 5,000 sqft, there are still 0 new listings below 2,000 sqft. Most buildings in this market are around 2 floors. Most buildings in this region were built in 1983 and are Class B.
Health care is the dominant industry in this area. Commute by car is the most popular way to get to work amongst East of 101 folk. Commuting approximately 15 minutes a day is the norm for those who opt to reside in this part of town.