On average, listings lease in the $20's per square foot per year. The San Luis Obispo submarket is seeing a an increase in rates. In the last 3 months, the median rate rose $1 per sqft per year. That's a 3% increase in rent.
In the last 90 days, 62 listings have been made available, so you'll want to check back regularly for new listings. About 8% of the listings in the San Luis Obispo are subleases, so you will probably have to consider a longer term lease. There aren't many listings below 2,000 square feet available, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 1,330 sqft. Most buildings in this region are approximately 2 stories. Most buildings in this region were built in 2001 and are Class A.