Compared to the rest of the Bay Area market, the Noe Valley region has higher rates, and you'll need to make a great offer to be in this hot region.
In the last 90 days, 2 listings have been made available, which means leases are probably leasing quickly. You'll want to be prepared to make an offer immediately. There aren't many listings below 2,000 square feet on the market, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 500 sqft. Most properties in this area are around 3 floors. Most buildings in this area were built in 1908 and are Class C.
Not much of the real estate is used for commercial space, so it might be hard to find office space. Education is the dominant industry in this region. Most of the folk of Noe Valley work from home. Commuting more than an hour and a half a day is the norm for those who opt to reside in this part of town.