The typical asking rate per listing is in the $60's per square foot per year. The Mission District region is going through a an increase in rates. In the last 3 months, the median rate went up $5 per sqft per year. That's a 8% rise in rent.
Compared to the rest of the Bay Area market, the Mission District submarket has more expensive rates, and you'll need to make a great offer to be in this hot submarket.
In the last 90 days, 27 listings have come on the market, which means leases most likley are leasing quickly. You'll want to be prepared to tour spaces as quick as possible. About 15% of the office spaces in the Mission District are subleases, so you might be able to sign a shorter term by taking over a previous lease. There aren't many listings below 2,000 square feet available, so finding a space for a small business might be tough.
Even though the median size is 3,000 sqft, there are still 0 office spaces below 2,000 sqft. Most buildings in this region are approximately 2 floors. Most buildings in this market were built in 1914 and are Class B.
Not much of the real estate is used for commercial space, so it might be hard to find office space. Utilities is the dominant industry in this area. Commute by public transit is the most popular way to get to work amongst Mission District residents. Commuting around 10 minutes a day is the norm for those who opt to reside in this part of town.