The typical asking rate per listing is in the $20's per square foot per year. The Mission Valley West region is going through a decline in rates. In the last 3 months, the median rate fell $7 per sqft per year. That's a 22% decrease in rent.
Compared to the rest of the San Diego market, the Mission Valley West region has less expensive rates, so you should have no trouble finding a great deal in this depreciated submarket.
In the last 90 days, 5 listings have been made available, which means leases most likley are going fast. You'll want to be prepared to tour spaces as quick as possible. There aren't many listings below 2,000 square feet available, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 1,940 sqft. Most buildings in this area are close to 3 floors. Most buildings in this region were built in 1973 and are Class B.
Not much of the real estate is used for commercial space, so it might be hard to find office space. Construction is the dominant industry in this area. Most of the residents of Mission Valley West work from home. Commuting more than an hour and a half a day is the norm for those who opt to reside in this part of town.