On average, listings lease in the $20's per square foot per year. The La Mesa region is seeing a an increase in rates. In the last 3 months, the median rate rose $24 per sqft per year.
Compared to the rest of the San Diego market, the La Mesa submarket has less expensive rates, so you should have no trouble finding a great deal in this discounted region.
In the last 90 days, 11 listings have been posted online, which means new availabilities might be going fast. You'll want to be prepared to tour spaces as quick as possible. About 127% of the office spaces in the La Mesa are subleases, so you might be able to sign a shorter term by taking over a previous lease. There aren't many listings below 2,000 square feet available, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 2,310 sqft. Most properties in this area are close to 2 floors. Most buildings in this market were built in 1979 and are Class C.