On average, listings lease in the $20's per square foot per year. The Fresno region is going through a decline in rates. In the last 3 months, the median rate decreased $1 per sqft per year. That's a 4% decline in rent.
Compared to the rest of the Fresno market, the Fresno submarket has lower rates, so you should have no trouble finding a great deal in this undervalued region.
In the last 90 days, 233 listings have been made available, so you'll want to check back regularly for new listings. About 2% of the office spaces in the Fresno are subleases, so you will probably need to consider the implications of signing a direct lease with the building. There aren't many listings below 2,000 square feet on the market, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 1,620 sqft. Most properties in this area are around 1 stories. Most buildings in this region were built in 1981 and are Class B.