Compared to the rest of the Metropolitan Los Angeles market, the East Los Angeles submarket has lower rates, so you should have no trouble finding a great deal in this depreciated region.
In the last 90 days, 7 listings have been listed, which means leases most likley are leasing quickly. You'll want to be prepared to tour spaces as quick as possible. There aren't many listings below 2,000 square feet posted, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 740 sqft. Most buildings in this area are around 1 stories. Most buildings in this area were built in 1948 and are Class B.