On average, listings lease in the $40's per square foot per year. The Aliso Viejo region is going through a a boost in rates. In the last 3 months, the median rate rose $50 per sqft per year.
Compared to the rest of the Metropolitan Los Angeles market, the Aliso Viejo region has higher rates, and you'll have to negotiate above asking rent to be in this hot submarket.
In the last 90 days, 11 listings have come on the market, which means listings most likley are leasing quickly. You'll want to be prepared to tour spaces as quick as possible. About 73% of the listings in the Aliso Viejo are subleases, so you might be able to sign a shorter term by taking over a previous lease. There aren't many listings below 2,000 square feet on the market, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 2,190 sqft. Most buildings in this region are close to 2 stories. Most buildings in this market were built in 1999 and are Class B.