In the last 90 days, 1 listings have been posted online, which means new listings most likley are going fast. You'll want to be prepared to make an offer immediately. About 200% of the available space in the South End are subleases, so you might be able to find a shorter term or below market rent. There aren't many listings below 2,000 square feet posted, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around sqft. Most properties in this market are close to 4 stories. Most buildings in this market were built in 1945.
Not much of the real estate is used for commercial space, so it might be hard to find office space. Public administration is the dominant industry in this area. Most of the occupants of South End work from home. Commuting approximately 30 minutes a day is the norm for those who opt to reside in this part of town.