On average, listings lease in the $20's per square foot per year. The Center City region is going through a an increase in rates. In the last 3 months, the median rate increased $1 per sqft per year. That's a 5% rise in rent.
In the last 90 days, 94 listings have come on the market, so you'll want to check back regularly for new listings. About 22% of the available leases in the Center City are subleases, so you might be able to find a shorter term or below market rent. There aren't many listings below 2,000 square feet posted, so finding a space for a small business might be tough.
Even though the median size is 4,450 sqft, there are still 0 listings below 2,000 sqft. Most properties in this area are approximately 2 stories. Most buildings in this market were built in 1946 and are Class C.
Professional services is the dominant industry in this region. Most of the folk of Center City work from home. Commuting under 5 minutes a day is the norm for those who opt to reside in this part of town.