On average, listings lease in the $20's per square foot per year. The Knoxville region is experiencing a decline in rates. In the last 3 months, the median rate fell $3 per sqft per year. That's a 13% decline in rent.
In the last 90 days, 50 listings have been made available, so you'll want to check back regularly for new listings. About 10% of the listings in the Knoxville are subleases, so you will probably have to focus your search on direct office leases. There aren't many listings below 2,000 square feet posted, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 2,250 sqft. Most properties in this area are around 1 floors. Most buildings in this area were built in 1899 and are Class Class B.