Most listings are in the $20's per square foot per year. The South Carolina region is going through a an increase in rates. In the last 3 months, the median rate went up $3 per sqft per year. That's a 12% increase in rent.
In the last 90 days, 760 listings have been posted online, so you'll want to check back regularly for new listings. About 3% of the available leases in the South Carolina are subleases, so you will probably have to consider a longer term lease. There aren't many listings below 2,000 square feet posted, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 2,400 sqft. Most properties in this region are approximately 2 floors. Most buildings in this area were built in 1988 and are Class B.