On average, listings lease in the $10's per square foot per year. The Uptown region is going through a an increase in rates. In the last 3 months, the median rate rose $15 per sqft per year.
In the last 90 days, 10 listings have been posted online, which means spaces are probably going fast. You'll want to be prepared to make an offer immediately. About 20% of the listings in the Uptown are subleases, so you might be able to snag a great spot on a short term. There aren't many listings below 2,000 square feet on the market, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 2,320 sqft. Most properties in this area are around 3 floors. Most buildings in this area were built in 1927 and are Class B.
Not much of the real estate is used for commercial space, so it might be hard to find office space. Health care is the dominant industry in this region. Commute by public transit is the most popular way to get to work amongst Uptown residents. Commuting around 15 minutes a day is the norm for those who opt to reside in this part of town.