The typical asking rate per listing is in the $10's per square foot per year. The Harrisburg region is seeing a an increase in rates. In the last 3 months, the median rate went up $1 per sqft per year. That's a 4% rise in rent.
In the last 90 days, 18 listings have been listed, which means spaces are probably going fast. You'll want to be prepared to tour spaces as quick as possible. About 6% of the listings in the Harrisburg are subleases, so you will probably need to consider the implications of signing a direct lease with the building. There aren't many listings below 2,000 square feet on the market, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 2,470 sqft. Most buildings in this region are around 3 stories. Most buildings in this market were built in 1936 and are Class B.