Compared to the rest of the New York City market, the South Bronx region has less expensive rates, so you should have no trouble finding a great deal in this depreciated region.
In the last 90 days, 24 listings have been posted online, which means leases are probably leasing quickly. You'll want to be prepared to tour spaces as quick as possible. There aren't many listings below 2,000 square feet on the market, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 1,940 sqft. Most properties in this area are close to 4 floors. Most buildings in this area were built in 1931 and are Class B.
Not much of the real estate is used for commercial space, so it might be hard to find office space. Public administration is the dominant industry in this area. Most of the residents of South Bronx work from home. Commuting around 10 minutes a day is the norm for those who opt to reside in this part of town.