The typical asking rate per listing is in the $180's per square foot per year. The Upper West Side region is going through a a boost in rates. In the last 3 months, the median rate went up $40 per sqft per year. That's a 27% rise in rent.
Compared to the rest of the New York City market, the Upper West Side region has greater rates, and you'll have to negotiate above asking rent to be in this hot submarket.
In the last 90 days, 38 listings have been posted online, which means spaces most likley are going fast. You'll want to be prepared to tour spaces as quick as possible. There aren't many listings below 2,000 square feet on the market, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 200 sqft. Most buildings in this area are around 6 stories. Most buildings in this area were built in 1920 and are Class A.
Not much of the real estate is used for commercial space, so it might be hard to find office space. Information is the dominant industry in this region. Most of the folk of Upper West Side work from home. Commuting close to 20 minutes a day is the norm for those who opt to reside in this part of town.