Most listings are in the $20's per square foot per year. The San Mateo region is going through a decrease in rates. In the last 3 months, the median rate decreased $4 per sqft per year. That's a 15% decline in rent.
In the last 90 days, 10 listings have come on the market, which means new availabilities are probably going fast. You'll want to be prepared to make an offer immediately. There aren't many listings below 2,000 square feet posted, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 1,690 sqft. Most properties in this market are close to 1 stories. Most buildings in this market were built in 1982 and are Class Class A.
Not much of the real estate is used for commercial space, so it might be hard to find office space. Health care is the dominant industry in this area. Most of the residents of San Mateo work from home. Commuting approximately 20 minutes a day is the norm for those who opt to reside in this part of town.