On average, listings lease in the $20's per square foot per year. The Winston-Salem region is going through a decline in rates. In the last 3 months, the median rate fell $0 per sqft per year. That's a 1% decrease in rent.
In the last 90 days, 74 listings have come on the market, so you'll want to check back regularly for new listings. About 4% of the listings in the Winston-Salem are subleases, so you will probably need to consider the implications of signing a direct lease with the building. There aren't many listings below 2,000 square feet on the market, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 2,400 sqft. Most buildings in this region are around 2 floors. Most buildings in this market were built in 1981 and are Class A.