Most listings are in the $10's per square foot per year. The Cape Girardeau submarket is experiencing a decrease in rates. In the last 3 months, the median rate fell $1 per sqft per year. That's a 7% decline in rent.
In the last 90 days, 5 listings have been made available, which means leases are probably going fast. You'll want to be prepared to make an offer immediately. There aren't many listings below 2,000 square feet posted, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 2,420 sqft. Most properties in this market are approximately 2 stories. Most buildings in this region were built in 1993 and are Class A.