Most listings are in the $10's per square foot per year. The Frederick region is seeing a decrease in rates. In the last 3 months, the median rate decreased $3 per sqft per year. That's a 13% decrease in rent.
Compared to the rest of the Washington D.C. market, the Frederick submarket has smaller rates, so you should have no trouble finding a great deal in this undervalued submarket.
In the last 90 days, 20 listings have been listed, which means listings are probably going fast. You'll want to be prepared to make an offer immediately. About 5% of the office spaces in the Frederick are subleases, so you will probably need to consider the implications of signing a direct lease with the building. There aren't many listings below 2,000 square feet on the market, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 1,700 sqft. Most properties in this area are close to 2 stories. Most buildings in this area were built in 1984 and are Class A.