The typical asking rate per listing is in the $10's per square foot per year. The Lowell region is going through a decrease in rates. In the last 3 months, the median rate fell $1 per sqft per year. That's a 6% decrease in rent.
Compared to the rest of the Greater Boston market, the Lowell submarket has lower rates, so you should have no trouble finding a great deal in this undervalued region.
In the last 90 days, 61 listings have been made available, so you'll want to check back regularly for new listings. There aren't many listings below 2,000 square feet available, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 1,630 sqft. Most properties in this area are approximately 4 stories. Most buildings in this area were built in 1977 and are Class B.