On average, listings lease in the $30's per square foot per year. The Barnstable Town submarket is going through a a rise in rates. In the last 3 months, the median rate increased $10 per sqft per year. That's a 36% increase in rent.
Compared to the rest of the Greater Boston market, the Barnstable Town region has more expensive rates, and you'll need to make a great offer to be in this hot region.
In the last 90 days, 14 listings have been made available, which means listings most likley are going fast. You'll want to be prepared to tour spaces as quick as possible. About 7% of the available leases in the Barnstable Town are subleases, so you will probably have to focus your search on direct office leases. There aren't many listings below 2,000 square feet available, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 770 sqft. Most properties in this area are around 2 stories. Most buildings in this area were built in 1987 and are Class B.