The typical asking rate per listing is in the $20's per square foot per year. The Mission submarket is seeing a decrease in rates. In the last 3 months, the median rate decreased $10 per sqft per year. That's a 30% decrease in rent.
In the last 90 days, 16 listings have been posted online, which means new availabilities are probably going fast. You'll want to be prepared to make an offer immediately. There aren't many listings below 2,000 square feet available, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 2,470 sqft. Most properties in this region are around 2 floors. Most buildings in this area were built in 1972 and are Class B.