Most listings are in the $10's per square foot per year. The Manhattan region is going through a decrease in rates. In the last 3 months, the median rate fell $1 per sqft per year. That's a 7% decline in rent.
In the last 90 days, 10 listings have come on the market, which means listings might be going fast. You'll want to be prepared to make an offer immediately. There aren't many listings below 2,000 square feet posted, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 950 sqft. Most properties in this region are close to 2 floors. Most buildings in this market were built in 1984 and are Class A.