Most listings are in the $50's per square foot per year. The Ames region is seeing a a boost in rates. In the last 3 months, the median rate went up $34 per sqft per year. That's a 209% increase in rent.
In the last 90 days, 13 listings have been listed, which means spaces most likley are leasing quickly. You'll want to be prepared to tour spaces as quick as possible. About 8% of the office spaces in the Ames are subleases, so you will probably have to consider a longer term lease. There aren't many listings below 2,000 square feet posted, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 350 sqft. Most buildings in this area are approximately 1 floors. Most buildings in this area were built in 2001 and are Class B.