Most listings are in the $10's per square foot per year. The Estero submarket is going through a an increase in rates. In the last 3 months, the median rate rose $18 per sqft per year.
In the last 90 days, 10 listings have been listed, which means leases most likley are leasing quickly. You'll want to be prepared to tour spaces as quick as possible. About 80% of the listings in the Estero are subleases, so you might be able to snag a great spot on a short term. There aren't many listings below 2,000 square feet available, so finding a space for a small business might be tough.
Even though the median size is 16,050 sqft, there are still 0 leases below 2,000 sqft. Most properties in this area are around 3 stories. Most buildings in this area were built in 2003 and are Class A.