On average, listings lease in the $20's per square foot per year. The Columbine region is going through a an increase in rates. In the last 3 months, the median rate rose $23 per sqft per year. That's a Inf% rise in rent.
Compared to the rest of the Denver Metro market, the Columbine submarket has smaller rates, so you should have no trouble finding a great deal in this discounted region.
In the last 90 days, 3 listings have come on the market, which means listings are probably leasing quickly. You'll want to be prepared to make an offer immediately. There aren't many listings below 2,000 square feet available, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 1,340 sqft. Most buildings in this market were built in 1985.