The typical asking rate per listing is in the $10's per square foot per year. The Santee region is seeing a a boost in rates. In the last 3 months, the median rate went up $18 per sqft per year.
Compared to the rest of the San Diego market, the Santee region has less expensive rates, so you should have no trouble finding a great deal in this depreciated region.
In the last 90 days, 2 listings have been posted online, which means office spaces are probably going fast. You'll want to be prepared to make an offer immediately. There aren't many listings below 2,000 square feet posted, so finding a space for a small business might be tough.
Even though the median size is 2,700 sqft, there are still 0 new availabilities below 2,000 sqft. Most properties in this region are around 2 stories. Most buildings in this region were built in 1973 and are Class C.