On average, listings lease in the $10's per square foot per year. The Santee region is experiencing a decrease in rates. In the last 3 months, the median rate decreased $2 per sqft per year. That's a 10% decrease in rent.
Compared to the rest of the San Diego market, the Santee region has less expensive rates, so you should have no trouble finding a great deal in this depreciated region.
In the last 90 days, 2 listings have been made available, which means new availabilities might be leasing quickly. You'll want to be prepared to make an offer immediately. There aren't many listings below 2,000 square feet posted, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 1,000 sqft. Most buildings in this market are approximately 2 stories. Most buildings in this area were built in 1972 and are Class C.