Most listings are in the $20's per square foot per year. The Santa Cruz submarket is experiencing a an increase in rates. In the last 3 months, the median rate increased $3 per sqft per year. That's a 14% rise in rent.
In the last 90 days, 32 listings have been posted online, which means new listings most likley are leasing quickly. You'll want to be prepared to make an offer immediately. There aren't many listings below 2,000 square feet available, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 1,590 sqft. Most properties in this area are around 2 stories. Most buildings in this area were built in 1972 and are Class B.