The typical asking rate per listing is in the $20's per square foot per year. The San Luis Obispo submarket is experiencing a an increase in rates. In the last 3 months, the median rate increased $3 per sqft per year. That's a 12% increase in rent.
In the last 90 days, 27 listings have been made available, which means leases might be leasing quickly. You'll want to be prepared to tour spaces as quick as possible. About 15% of the available space in the San Luis Obispo are subleases, so you might be able to snag a great spot on a short term. There aren't many listings below 2,000 square feet available, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 2,020 sqft. Most properties in this market are around 2 floors. Most buildings in this area were built in 2000 and are Class A.