On average, listings lease in the $20's per square foot per year. The San Luis Obispo region is going through a a boost in rates. In the last 3 months, the median rate rose $4 per sqft per year. That's a 17% rise in rent.
In the last 90 days, 20 listings have been listed, which means office spaces most likley are going fast. You'll want to be prepared to tour spaces as quick as possible. There aren't many listings below 2,000 square feet posted, so finding a space for a small business might be tough.
Even though the median size is 3,140 sqft, there are still 0 listings below 2,000 sqft. Most properties in this region are approximately 2 floors. Most buildings in this area were built in 2009 and are Class A.