Most listings are in the $20's per square foot per year. The Southern San Diego submarket is going through a an increase in rates. In the last 3 months, the median rate went up $29 per sqft per year.
Compared to the rest of the San Diego market, the Southern San Diego region has lower rates, so you should have no trouble finding a great deal in this discounted region.
In the last 90 days, 16 listings have been made available, which means spaces might be leasing quickly. You'll want to be prepared to tour spaces as quick as possible. About 113% of the available space in the Southern San Diego are subleases, so you might be able to snag a great spot on a short term. There aren't many listings below 2,000 square feet posted, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 1,000 sqft. Most buildings in this area are close to 2 stories. Most buildings in this market were built in 1989 and are Class A.
Not much of the real estate is used for commercial space, so it might be hard to find office space. Information is the dominant industry in this region. Commute by car is the most popular way to get to work amongst Southern San Diego folk. Commuting between 20 and 25 minutes a day is the norm for those who opt to reside in this part of town.