Most listings are in the $20's per square foot per year. The Southern San Diego submarket is going through a a boost in rates. In the last 3 months, the median rate went up $29 per sqft per year.
Compared to the rest of the San Diego market, the Southern San Diego submarket has smaller rates, so you should have no trouble finding a great deal in this discounted region.
In the last 90 days, 16 listings have been made available, which means listings most likley are going fast. You'll want to be prepared to make an offer immediately. About 81% of the available space in the Southern San Diego are subleases, so you might be able to snag a great spot on a short term. There aren't many listings below 2,000 square feet posted, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 980 sqft. Most properties in this market are around 2 floors. Most buildings in this market were built in 1989 and are Class A.
Not much of the real estate is used for commercial space, so it might be hard to find office space. Information is the dominant industry in this area. Commute by car is the most popular way to get to work amongst Southern San Diego residents. Commuting between 20 and 25 minutes a day is the norm for those who opt to reside in this part of town.