Most listings are in the $10's per square foot per year. The Palmdale region is seeing a decrease in rates. In the last 3 months, the median rate decreased $10 per sqft per year. That's a 35% decrease in rent.
Compared to the rest of the Metropolitan Los Angeles market, the Palmdale submarket has smaller rates, so you should have no trouble finding a great deal in this discounted region.
In the last 90 days, 4 listings have been listed, which means leases most likley are going fast. You'll want to be prepared to make an offer immediately. There aren't many listings below 2,000 square feet available, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 1,430 sqft. Most buildings in this market are around 2 stories. Most buildings in this region were built in 2006 and are Class A.