The typical asking rate per listing is in the $10's per square foot per year. The Palmdale region is experiencing a decline in rates. In the last 3 months, the median rate fell $4 per sqft per year. That's a 20% decline in rent.
Compared to the rest of the Metropolitan Los Angeles market, the Palmdale submarket has smaller rates, so you should have no trouble finding a great deal in this depreciated submarket.
In the last 90 days, 6 listings have been listed, which means listings are probably going fast. You'll want to be prepared to make an offer immediately. There aren't many listings below 2,000 square feet on the market, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 1,100 sqft. Most properties in this market are close to 2 floors. Most buildings in this area were built in 1998 and are Class A.