Most listings are in the $10's per square foot per year. The Mendocino region is seeing a an increase in rates. In the last 3 months, the median rate rose $17 per sqft per year. That's a Inf% increase in rent.
In the last 90 days, 4 listings have been listed, which means new availabilities most likley are going fast. You'll want to be prepared to tour spaces as quick as possible. There aren't many listings below 2,000 square feet on the market, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 740 sqft. Most properties in this region are around 1 stories.